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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Diffuse noxious inhibitory control ： ウィキペディア英語版 Diffuse noxious inhibitory control Diffuse Noxious Inhibitory Controls (DNIC) refers to an endogenous pain modulatory pathway which has often been described as "pain inhibits pain".〔Le Bars D, Dickenson AH, Besson JM (June 1979). "Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat". ''Pain'' 6 (3): 283–304. PMID 460935.〕 It occurs when response from a painful stimulus is inhibited by another, often spatially distant, noxious stimulus. ==Mechanism== Noxious stimuli activate the endings of nociceptive C and A delta nerve fibers, which carry the signal to neurons in the dorsal horn of spinal cord. DNIC refers to the mechanism by which dorsal horn wide dynamic range neurons responsive to stimulation from one location of the body may be inhibited by noxious stimuli (such as heat, high pressure or electric stimulation) applied to another, remote location in the body.〔 The inhibition is thought to originate in the brain, and is thought to affect both wide dynamic range and nociception-specific neurons in the dorsal horn〔 Le Bars D (October 2002). "The whole body receptive field of dorsal horn multireceptive neurones". ''Brain Research. Brain Research Reviews'' 40 (1-3): 29–44. PMID 12589904〕 Studies investigating gender differences in DNIC have shown mixed results with the effect dependent upon experimental methodology and measurement method.〔Popescu A, LeResche L, Truelove EL, Drangsholt MT (August 2010). "Gender differences in pain modulation by diffuse noxious inhibitory controls: a systematic review". ''Pain'' 150 (2): 309–18. . PMID 20557999.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Diffuse noxious inhibitory control」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.